{"id":1019,"date":"2020-02-17T14:17:10","date_gmt":"2020-02-17T14:17:10","guid":{"rendered":"https:\/\/vetomshop.hu\/?page_id=1019"},"modified":"2024-05-23T10:56:21","modified_gmt":"2024-05-23T08:56:21","slug":"a-vetom-probiotikum-tortenete","status":"publish","type":"page","link":"https:\/\/vetomshop.hu\/lv\/a-vetom-probiotikum-tortenete\/","title":{"rendered":"Vetom probiotikas v\u0113sture"},"content":{"rendered":"

A Bacillus<\/em> Bakt\u0113riju un pirmo \u201edz\u012bvo\u201d prepar\u0101tu, kuru pamat\u0101 bija bakt\u0113rijas, p\u0113t\u012bjumi s\u0101k\u0101s 20. gadsimta 30. gados.<\/h3>\n

\"\"1939. gad\u0101 Vermachta karasp\u0113ks \u0100frik\u0101 sask\u0101r\u0101s ar dizent\u0113rijas probl\u0113mu. Slim\u012bba sk\u0101ra abu pu\u0161u armijas. Pirmie slim\u012bbu izskauda ar\u0101bi. K\u0101 efekt\u012bvs medikaments tika izmantoti kamie\u013cu m\u0113sli. V\u0101cie\u0161i atteic\u0101s lietot kamie\u013cu m\u0113slus, ta\u010du vi\u0146i atkl\u0101ja \u0161\u012b l\u012bdzek\u013ca lielisko efektivit\u0101ti. Akt\u012bv\u0101 viela ir\u00a0 Bacillus subtilis<\/em> mikroorganisms, kas sp\u0113j nom\u0101kt dizent\u0113rijas patog\u0113nu att\u012bst\u012bbu un vairo\u0161anos. Pamatojoties uz \u0161o bakt\u0113riju, v\u0101cu zin\u0101tnieki rad\u012bja probiotikas prepar\u0101tu, ko v\u0113l\u0101k pla\u0161i izmantoja armij\u0101 dizent\u0113rijas profilaksei. P\u0113c Hitlera V\u0101cijas sabrukuma probiotika ra\u017eo\u0161anas tehnolo\u0123iju ieg\u0101d\u0101j\u0101s amerik\u0101\u0146i.<\/p>\n

Tom\u0113r Padomju Savien\u012bba nepalika mal\u0101.<\/h3>\n

Otr\u0101 pasaules kara beig\u0101s tika mobiliz\u0113ti lieli sp\u0113ki aizsardz\u012bbai pret modernajiem iero\u010diem, tostarp biolo\u0123iskajiem iero\u010diem. 1974. gad\u0101 tika izveidota milz\u012bga slepena organiz\u0101cija - Mikrobioproms -, lai izstr\u0101d\u0101tu prepar\u0101tus cilv\u0113ku aizsardz\u012bbai pret biog\u0113n\u0101m katastrof\u0101m, tostarp biolo\u0123iskajiem iero\u010diem. Mikrobioproma sist\u0113m\u0101 ietilpa tolaik past\u0101vo\u0161ie zin\u0101tniskie instit\u016bti, k\u0101 ar\u012b jaunizveidotie specializ\u0113tie zin\u0101tniskie mikrobiolo\u0123ijas centri un biolo\u0123isk\u0101s ra\u017eo\u0161anas r\u016bpn\u012bcas. Mikrobioproma vado\u0161\u0101 iest\u0101de bija uz\u0146\u0113mums \u201eVektor\u201d, kas atrad\u0101s Kolcova ciemat\u0101 net\u0101lu no Novosibirskas. \u0160\u012bs iest\u0101des izm\u0113ri v\u0113l \u0161odien ir iespaid\u012bgi. Paral\u0113li \u201eVektor\u201d tika b\u016bv\u0113tas un att\u012bst\u012btas v\u0113l piecas citas iest\u0101des. T\u0101d\u0113j\u0101di sal\u012bdzino\u0161i \u012bs\u0101 laik\u0101 Padomju Savien\u012bba k\u013cuva par pasaules l\u012bderi mikrobiolo\u0123ij\u0101.<\/p>\n

\"\"Jo \u012bpa\u0161i 90. gadu s\u0101kum\u0101 \u201eVector\u201d k\u013cuva par pirmo cilv\u0113ku v\u0113stur\u0113, kas veiksm\u012bgi rad\u012bja m\u0101ksl\u012bgu dz\u012bvu objektu - \u201eplazm\u012bdu\u201e -, kas \u0123ener\u0113 cilv\u0113ka leikoc\u012btu interferonu alfa-2, b\u016btisku im\u016bnsist\u0113mas olbaltumvielu, kas tika veiksm\u012bgi iestr\u0101d\u0101ta im\u016bnsist\u0113m\u0101. \u00a0Bacillus subtilis<\/em> mikrovi\u013c\u0146u kamer\u0101. Rezult\u0101t\u0101 ir rad\u012bta rekombinant\u0101 versija, kas var ra\u017eot aptuveni 70 antibiotikas, k\u0101 ar\u012b pla\u0161u fermentu un interferonu kl\u0101stu. \u0160is celms sporul\u0113, bez boj\u0101jumiem iek\u013c\u016bst ku\u0146\u0123a un divpadsmitpirkstu zarnas g\u013cot\u0101d\u0101 un aktiviz\u0113jas resnaj\u0101 zarn\u0101.<\/p>\n

\u0160is probiotikas prepar\u0101ts, kura pamat\u0101 ir iepriek\u0161 min\u0113tais probiotikas prepar\u0101ts, tiek saukts \u201eSubalin\u201d. Un kas notika t\u0101l\u0101k, visi zina. Padomju Savien\u012bba r\u012bkoj\u0101s nepareizi, s\u0101k\u0101s tirgus reformas, un vara nev\u0113l\u0113j\u0101s \u201eMicrobioprom\u201d. Bet ASV vald\u012bbai vajadz\u0113ja \u201eVektoru\u201d. Tr\u012bs gadus \u0101rvalstu eksperti p\u0113t\u012bja, p\u0101rbaud\u012bja un v\u0101ca datus \u201eVektora\u201d jom\u0101. Protams, Subalin nevar\u0113ja iek\u013c\u016bt tirg\u016b. Par to, ka vismaz da\u013ca \u201eVektora\u201d p\u0113t\u012bjumu netika pazaud\u0113ta, liel\u0101 m\u0113r\u0101 j\u0101pateicas t\u0101 rad\u012bt\u0101jam \u013bevam Stepanovi\u010dam Sanah\u010dijevam - vienam no \u201eSubalina\u201d rad\u012bt\u0101jiem. No atsevi\u0161\u0137\u0101m \u201eVektora\u201d strukt\u016brvien\u012bb\u0101m Sanah\u010dijevs izveidoja vair\u0101kus priv\u0101tos uz\u0146\u0113mumus, kas iem\u0101c\u012bj\u0101s izdz\u012bvot priv\u0101taj\u0101 l\u012bnij\u0101. Aptuveni pusei no tiem tas izdev\u0101s.<\/p>\n

To vid\u016b ir Centr\u0101lais zin\u0101tniskais - \u201eP\u0113tniec\u012bbas centrs\u201d, kas, cita starp\u0101, ir paz\u012bstams ar mikrobiolo\u0123iju un \u0123en\u0113tiku, kur\u0101 mikrobiologs un \u0123en\u0113ti\u0137is Aleksandrs Ivanovi\u010ds Le\u013cjaks re\u0123istr\u0113jis vair\u0101k nek\u0101 50 izgudrojumu.<\/h3>\n

T\u0101 sagad\u012bj\u0101s, ka tie\u0161i \u0161is uz\u0146\u0113mums bija atbild\u012bgs par dz\u012bvo prepar\u0101tu t\u0113mu, to t\u0101l\u0101ku izp\u0113ti un rad\u012b\u0161anas organiz\u0113\u0161anu. P\u0113d\u0113jo 20 gadu laik\u0101 P\u0113tniec\u012bbas centrs, kur\u0101 pa\u0161laik str\u0101d\u0101 vair\u0101k nek\u0101 200 speci\u0101listu, ir izstr\u0101d\u0101jis strat\u0113\u0123iju, lai piel\u0101gotos pa\u0161reiz\u0113jiem tirgus apst\u0101k\u013ciem.<\/p>\n

\"\"Mikrobi veido 90 procentus m\u016bsu plan\u0113tas biomasas, skaidro Aleksandrs Ivanovi\u010ds Le\u013cjaks. - Varam dro\u0161i apgalvot, ka pasaule, kur\u0101 m\u0113s dz\u012bvojam, paties\u012bb\u0101 ir vi\u0146u pasaule. Liel\u0101k\u0101 da\u013ca mikroorganismu - cilv\u0113ku, dz\u012bvnieku un augu infekcijas. M\u0113s pa\u0161i esam 2-3 procenti mikrobu. Ja m\u0113s apl\u016bkojam jebkuru sava \u0137erme\u0146a da\u013cu, redzam, ka tur past\u0101v noteikti mikroorganismi - katrai \u0137erme\u0146a da\u013cai ir sava mikrobu ekosist\u0113ma. Tie pal\u012bdz organismam aizsarg\u0101ties pret apk\u0101rt\u0113j\u0101s vides kait\u012bgo ietekmi. Ja m\u0113s to p\u0101rk\u0101pjam - m\u0113s saslimstam. Tom\u0113r optim\u0101l\u0101 gad\u012bjum\u0101, kad visi m\u016bsu pa\u0161u mikrobi paliek kop\u0101 ar mums, m\u0113s sp\u0113jam sevi pasarg\u0101t no vis\u0101m infekcij\u0101m!<\/p>","protected":false},"excerpt":{"rendered":"

A Bacillus bakt\u00e9riumok ut\u00e1n t\u00f6rt\u00e9n\u0151 kutat\u00e1sok \u00e9s azok alapj\u00e1n l\u00e9trehozott els\u0151 \u201e\u00e9l\u0151\u201d k\u00e9sz\u00edtm\u00e9nyek az 1930-as \u00e9vekre tehet\u0151. 1939-ben a Wermacht seregei Afrik\u00e1ban tal\u00e1lkoztak a v\u00e9rhas probl\u00e9m\u00e1j\u00e1val. A megbeteged\u00e9s \u00e9rintette mindk\u00e9t f\u00e9l sereg\u00e9t. A bajt els\u0151nek az arabok sz\u00fcntett\u00e9k meg. Hat\u00e9kony gy\u00f3gy k\u00e9sz\u00edtm\u00e9nyk\u00e9nt a tev\u00e9k tr\u00e1gy\u00e1j\u00e1t alkalmazt\u00e1k. A n\u00e9metek a tevetr\u00e1gy\u00e1t nem voltak hajland\u00f3k fogyasztani, viszont […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1019","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/pages\/1019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/comments?post=1019"}],"version-history":[{"count":0,"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/pages\/1019\/revisions"}],"wp:attachment":[{"href":"https:\/\/vetomshop.hu\/lv\/wp-json\/wp\/v2\/media?parent=1019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}