{"id":1019,"date":"2020-02-17T14:17:10","date_gmt":"2020-02-17T14:17:10","guid":{"rendered":"https:\/\/vetomshop.hu\/?page_id=1019"},"modified":"2024-05-23T10:56:21","modified_gmt":"2024-05-23T08:56:21","slug":"a-vetom-probiotikum-tortenete","status":"publish","type":"page","link":"https:\/\/vetomshop.hu\/sk\/a-vetom-probiotikum-tortenete\/","title":{"rendered":"Hist\u00f3ria probiotika Vetom"},"content":{"rendered":"

A Bacillus<\/em> v\u00fdskum bakt\u00e9ri\u00ed a prv\u00fdch \u201e\u017eiv\u00fdch\u201d pr\u00edpravkov na ich b\u00e1ze sa datuje do 30. rokov 20. storo\u010dia.<\/h3>\n

\"\"V roku 1939 sa jednotky Wermachtu stretli v Afrike s probl\u00e9mom \u00faplavice. T\u00e1to choroba postihla arm\u00e1dy oboch str\u00e1n. Prv\u00ed, ktor\u00ed chorobu zlikvidovali, boli Arabi. Ako \u00fa\u010dinn\u00fd liek sa pou\u017e\u00edval \u0165av\u00ed trus. Nemci odmietali konzumova\u0165 \u0165av\u00ed trus, ale zistili vynikaj\u00facu \u00fa\u010dinnos\u0165 tohto lieku. \u00da\u010dinnou zlo\u017ekou je\u00a0 Bacillus subtilis<\/em> mikroorganizmus schopn\u00fd potl\u00e1\u010da\u0165 v\u00fdvoj a rozmno\u017eovanie patog\u00e9nov dyzent\u00e9rie. Na z\u00e1klade tejto bakt\u00e9rie vytvorili nemeck\u00ed vedci probiotick\u00fd pr\u00edpravok, ktor\u00fd sa n\u00e1sledne \u0161iroko pou\u017e\u00edval v arm\u00e1de na prevenciu \u00faplavice. Po rozpade hitlerovsk\u00e9ho Nemecka z\u00edskali technol\u00f3giu na v\u00fdrobu tohto probiotika Ameri\u010dania.<\/p>\n

Sovietsky zv\u00e4z v\u0161ak nezostal ne\u010dinn\u00fd.<\/h3>\n

Na konci druhej svetovej vojny boli zmobilizovan\u00e9 ve\u013ek\u00e9 sily na obranu proti modern\u00fdm zbraniam vr\u00e1tane biologick\u00fdch zbran\u00ed. V roku 1974 bola zalo\u017een\u00e1 obrovsk\u00e1 tajn\u00e1 organiz\u00e1cia - Mikrobioprom -, ktor\u00e1 mala vyvin\u00fa\u0165 pr\u00edpravky na ochranu \u013eud\u00ed pred biog\u00e9nnymi katastrofami vr\u00e1tane biologick\u00fdch zbran\u00ed. Syst\u00e9m Mikrobiopromu zah\u0155\u0148al vtedaj\u0161ie vedeck\u00e9 \u00fastavy, ako aj novovytvoren\u00e9 \u0161pecializovan\u00e9 vedeck\u00e9 mikrobiologick\u00e9 centr\u00e1 a tov\u00e1rne na v\u00fdrobu biopotrav\u00edn. Ved\u00facou in\u0161tit\u00faciou Mikrobiopromu bola spolo\u010dnos\u0165 \u201eVektor\u201d, ktor\u00e1 sa nach\u00e1dzala v obci Kolcovo pri Novosibirsku. Rozloha tohto zariadenia je dodnes impozantn\u00e1. S\u00fabe\u017ene s podnikom Vektor bolo vybudovan\u00fdch a rozv\u00edjalo sa p\u00e4\u0165 \u010fal\u0161\u00edch in\u0161tit\u00faci\u00ed. V pomerne kr\u00e1tkom \u010dase sa tak Sovietsky zv\u00e4z stal svetov\u00fdm l\u00eddrom v mikrobiol\u00f3gii.<\/p>\n

\"\"Konkr\u00e9tne za\u010diatkom 90. rokov 20. storo\u010dia sa \u201evektorom\u201d ako prv\u00fdm v hist\u00f3rii \u013eudstva podarilo \u00faspe\u0161ne vytvori\u0165 umel\u00fd \u017eiv\u00fd objekt - \u201eplazmid\u201e, ktor\u00fd generuje \u013eudsk\u00fd leukocyt\u00e1rny interfer\u00f3n alfa-2, z\u00e1kladn\u00fd prote\u00edn imunitn\u00e9ho syst\u00e9mu, ktor\u00fd bol \u00faspe\u0161ne za\u010dlenen\u00fd do \u00a0Bacillus subtilis<\/em> v mikrovlnnej komore. V\u00fdsledkom je rekombinantn\u00e1 verzia, ktor\u00e1 dok\u00e1\u017ee produkova\u0165 pribli\u017ene 70 antibiot\u00edk, ako aj \u0161irok\u00fa \u0161k\u00e1lu fermentov a interfer\u00f3nov. Tento kme\u0148 je sporulovan\u00fd, prenik\u00e1 cez sliznicu \u017eal\u00fadka a dvan\u00e1stnika bez po\u0161kodenia a aktivuje sa v hrubom \u010dreve.<\/p>\n

Tento probiotick\u00fd pr\u00edpravok, zalo\u017een\u00fd na vy\u0161\u0161ie uvedenom probiotiku, sa naz\u00fdva \u201eSubalin\u201d. A \u010do sa stalo potom, ka\u017ed\u00fd vie. Sovietsky zv\u00e4z urobil chybu, za\u010dali sa trhov\u00e9 reformy a \u00farady nechceli Microbioprom. Ale vl\u00e1da USA potrebovala \u201eVektor\u201d. Tri roky zahrani\u010dn\u00ed experti \u0161tudovali, kontrolovali a zbierali \u00fadaje v oblasti \u201eVektor\u201d. Samozrejme, Subalin nemohol prenikn\u00fa\u0165 na trh. Aby sa aspo\u0148 \u010das\u0165 v\u00fdskumu \u201eVektora\u201d nestratila, za to patr\u00ed ve\u013ek\u00e1 v\u010faka jeho tvorcovi Levovi Stepanovi\u010dovi Sanach\u010devovi - jedn\u00e9mu z tvorcov \u201eSubalinu\u201d. Zo samostatn\u00fdch jednotiek spolo\u010dnosti Vektor vytvoril Sanhakchiev nieko\u013eko s\u00fakromn\u00fdch spolo\u010dnost\u00ed, ktor\u00e9 sa nau\u010dili pre\u017ei\u0165 na s\u00fakromnej linke. Pribli\u017ene polovici z nich sa to podarilo.<\/p>\n

Patr\u00ed k nim aj \u00dastredn\u00e9 vedeck\u00e9 - \u201eV\u00fdskumn\u00e9 centrum\u201d, ktor\u00e9 sa okrem in\u00e9ho vyzna\u010duje mikrobiol\u00f3giou a genetikou, pri\u010dom mikrobiol\u00f3g a genetik Alexander Ivanovi\u010d Lelyak tu zaregistroval viac ako 50 vyn\u00e1lezov.<\/h3>\n

Pr\u00e1ve t\u00e1to spolo\u010dnos\u0165 bola zodpovedn\u00e1 za predmet \u017eiv\u00fdch pr\u00edpravkov, ich \u010fal\u0161ie \u0161t\u00fadium a organiz\u00e1ciu ich tvorby. Za posledn\u00fdch 20 rokov v\u00fdskumn\u00e9 centrum, ktor\u00e9 v s\u00fa\u010dasnosti zamestn\u00e1va viac ako 200 odborn\u00edkov, vypracovalo strat\u00e9giu, ktor\u00e1 sa prisp\u00f4sobuje s\u00fa\u010dasn\u00fdm podmienkam na trhu.<\/p>\n

\"\"Mikr\u00f3by tvoria 90 percent biomasy na\u0161ej plan\u00e9ty, vysvet\u013euje Alexander Ivanovi\u010d Lelyak. - M\u00f4\u017eeme pokojne poveda\u0165, \u017ee svet, v ktorom \u017eijeme, je vlastne ich svetom. V\u00e4\u010d\u0161ina mikroorganizmov - \u013eudsk\u00e9, \u017eivo\u010d\u00ed\u0161ne a rastlinn\u00e9 infekcie. My sami tvor\u00edme 2 a\u017e 3 percent\u00e1 mikr\u00f3bov. Ak sa pozrieme na ktor\u00fako\u013evek \u010das\u0165 n\u00e1\u0161ho tela, vid\u00edme, \u017ee tam existuj\u00fa ur\u010dit\u00e9 mikroorganizmy - ka\u017ed\u00e1 \u010das\u0165 tela m\u00e1 svoj vlastn\u00fd mikrobi\u00e1lny ekosyst\u00e9m. Tie pom\u00e1haj\u00fa telu br\u00e1ni\u0165 sa proti \u0161kodliv\u00fdm vplyvom prostredia. Ak to poru\u0161\u00edme - ochorieme. V optim\u00e1lnom pr\u00edpade, ke\u010f s nami zost\u00e1vaj\u00fa v\u0161etky na\u0161e vlastn\u00e9 mikr\u00f3by, sa v\u0161ak dok\u00e1\u017eeme ochr\u00e1ni\u0165 pred v\u0161etk\u00fdmi infekciami!<\/p>","protected":false},"excerpt":{"rendered":"

A Bacillus bakt\u00e9riumok ut\u00e1n t\u00f6rt\u00e9n\u0151 kutat\u00e1sok \u00e9s azok alapj\u00e1n l\u00e9trehozott els\u0151 \u201e\u00e9l\u0151\u201d k\u00e9sz\u00edtm\u00e9nyek az 1930-as \u00e9vekre tehet\u0151. 1939-ben a Wermacht seregei Afrik\u00e1ban tal\u00e1lkoztak a v\u00e9rhas probl\u00e9m\u00e1j\u00e1val. A megbeteged\u00e9s \u00e9rintette mindk\u00e9t f\u00e9l sereg\u00e9t. A bajt els\u0151nek az arabok sz\u00fcntett\u00e9k meg. Hat\u00e9kony gy\u00f3gy k\u00e9sz\u00edtm\u00e9nyk\u00e9nt a tev\u00e9k tr\u00e1gy\u00e1j\u00e1t alkalmazt\u00e1k. A n\u00e9metek a tevetr\u00e1gy\u00e1t nem voltak hajland\u00f3k fogyasztani, viszont […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1019","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/pages\/1019","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/comments?post=1019"}],"version-history":[{"count":0,"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/pages\/1019\/revisions"}],"wp:attachment":[{"href":"https:\/\/vetomshop.hu\/sk\/wp-json\/wp\/v2\/media?parent=1019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}